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The DNA primase of Sulfolobus solfataricus is activated by substrates containing a thymine-rich bubble and has a 3′-terminal nucleotidyl-transferase activity

DNA primases are responsible for the synthesis of the short RNA primers that are used by the replicative DNA polymerases to initiate DNA synthesis on the leading- and lagging-strand at the replication fork. In this study, we report the purification and biochemical characterization of a DNA primase (...

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Bibliografske podrobnosti
Main Authors: De Falco, Mariarosaria, Fusco, Alessandra, De Felice, Mariarita, Rossi, Mosè, Pisani, Francesca M.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2004
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC521673/
https://ncbi.nlm.nih.gov/pubmed/15459292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh865
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