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The tyrocidine biosynthesis operon of Bacillus brevis: complete nucleotide sequence and biochemical characterization of functional internal adenylation domains.

The cyclic decapeptide antibiotic tyrocidine is produced by Bacillus brevis ATCC 8185 on an enzyme complex comprising three peptide synthetases, TycA, TycB, and TycC (tyrocidine synthetases 1, 2, and 3), via the nonribosomal pathway. However, previous molecular characterization of the tyrocidine syn...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Mootz, H D, Marahiel, M A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1997
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179617/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9352938/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.21.6843-6850.1997
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