The tyrocidine biosynthesis operon of Bacillus brevis: complete nucleotide sequence and biochemical characterization of functional internal adenylation domains.

The cyclic decapeptide antibiotic tyrocidine is produced by Bacillus brevis ATCC 8185 on an enzyme complex comprising three peptide synthetases, TycA, TycB, and TycC (tyrocidine synthetases 1, 2, and 3), via the nonribosomal pathway. However, previous molecular characterization of the tyrocidine syn...

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Bibliografische gegevens
Hoofdauteurs: Mootz, H D, Marahiel, M A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1997
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC179617/
https://ncbi.nlm.nih.gov/pubmed/9352938
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