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Targeted disruption of the β adducin gene (Add2) causes red blood cell spherocytosis in mice

Adducins are a family of cytoskeleton proteins encoded by three genes (α, β, γ). In a comprehensive assay of gene expression, we show the ubiquitous expression of α- and γ-adducins in contrast to the restricted expression of β-adducin. β-adducin is expressed at high levels in brain and hematopoietic...

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Autori principali: Gilligan, Diana M., Lozovatsky, Larissa, Gwynn, Babette, Brugnara, Carlo, Mohandas, Narla, Peters, Luanne L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC17949/
https://ncbi.nlm.nih.gov/pubmed/10485892
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