A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages

Rhodococcus sp. strain RHA1, a soil bacterium related to Mycobacterium tuberculosis, degrades an exceptionally broad range of organic compounds. Transcriptomic analysis of cholesterol-grown RHA1 revealed a catabolic pathway predicted to proceed via 4-androstene-3,17-dione and 3,4-dihydroxy-9,10-seco...

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Autores principales: Van der Geize, Robert, Yam, Katherine, Heuser, Thomas, Wilbrink, Maarten H., Hara, Hirofumi, Anderton, Matthew C., Sim, Edith, Dijkhuizen, Lubbert, Davies, Julian E., Mohn, William W., Eltis, Lindsay D.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794314/
https://ncbi.nlm.nih.gov/pubmed/17264217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0605728104
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