NF-κB prevents β cell death and autoimmune diabetes in NOD mice

Whereas NF-κB has potent antiapoptotic function in most cell types, it was reported that in pancreatic β cells it serves a proapoptotic function and may contribute to the pathogenesis of autoimmune type 1 diabetes. To investigate the role of β cell NF-κB in autoimmune diabetes, we produced transgeni...

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Detalles Bibliográficos
Autores principales: Kim, Sunshin, Millet, Isabelle, Kim, Hun Sik, Kim, Ja Young, Han, Myoung Sook, Lee, Moon-Kyu, Kim, Kwang-Won, Sherwin, Robert S., Karin, Michael, Lee, Myung-Shik
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2007
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794308/
https://ncbi.nlm.nih.gov/pubmed/17267600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610690104
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