NF-κB Activation in Hypothalamic Pro-opiomelanocortin Neurons Is Essential in Illness- and Leptin-induced Anorexia

Anorexia and weight loss are prevalent in infectious diseases. To investigate the molecular mechanisms underlying these phenomena, we established animal models of infection-associated anorexia by administrating bacterial and viral products, lipopolysaccharide (LPS) and human immunodeficiency virus-1...

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Main Authors: Jang, Pil-Geum, Namkoong, Cherl, Kang, Gil Myoung, Hur, Man-Wook, Kim, Seung-Whan, Kim, Geun Hyang, Kang, Yeoungsup, Jeon, Min-Jae, Kim, Eun Hee, Lee, Myung-Shik, Karin, Michael, Baik, Ja-Hyun, Park, Joong-Yeol, Lee, Ki-Up, Kim, Young-Bum, Kim, Min-Seon
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Metabolism
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843220/
https://ncbi.nlm.nih.gov/pubmed/20097762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.070706
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