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Structural basis for nucleotide exchange on Gα(i) subunits and receptor coupling specificity
Heterotrimeric G proteins are molecular switches that relay information intracellularly in response to various extracellular signals. How ligand-activated G protein-coupled receptors act at a distance to exert exchange activity on the Gα nucleotide binding pocket is poorly understood. Here we descri...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1794300/ https://ncbi.nlm.nih.gov/pubmed/17264214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608599104 |
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