Improved glucose tolerance in acyl CoA:diacylglycerol acyltransferase 1-null mice is dependent on diet

BACKGROUND: Mice that lack acyl CoA:diacylglycerol acyltransferase (Dgat1(-/- )mice) are reported to have a reduced body fat content and improved glucose tolerance and insulin sensitivity. Studies so far have focussed on male null mice fed a high fat diet and there are few data on heterozygotes. We...

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Bibliografiske detaljer
Main Authors: Wang, Steven JY, Cornick, Claire, O'Dowd, Jacqueline, Cawthorne, Michael A, Arch, Jonathan RS
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794239/
https://ncbi.nlm.nih.gov/pubmed/17239230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-6-2
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