Role for protease activity in visceral pain in irritable bowel syndrome

Mediators involved in the generation of symptoms in patients with irritable bowel syndrome (IBS) are poorly understood. Here we show that colonic biopsy samples from IBS patients release increased levels of proteolytic activity (arginine cleavage) compared to asymptomatic controls. This was dependen...

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מידע ביבליוגרפי
Main Authors: Cenac, Nicolas, Andrews, Christopher N., Holzhausen, Marinella, Chapman, Kevin, Cottrell, Graeme, Andrade-Gordon, Patricia, Steinhoff, Martin, Barbara, Giovanni, Beck, Paul, Bunnett, Nigel W., Sharkey, Keith A., Ferraz, Jose Geraldo P., Shaffer, Eldon, Vergnolle, Nathalie
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Clinical Investigation 2007
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1794118/
https://ncbi.nlm.nih.gov/pubmed/17304351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29255
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