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Overexpression of the D-alanine racemase gene confers resistance to D-cycloserine in Mycobacterium smegmatis.

D-Cycloserine is an effective second-line drug against Mycobacterium avium and Mycobacterium tuberculosis. To analyze the genetic determinants of D-cycloserine resistance in mycobacteria, a library of a resistant Mycobacterium smegmatis mutant was constructed. A resistant clone harboring a recombina...

詳細記述

保存先:
書誌詳細
主要な著者: Cáceres, N E, Harris, N B, Wellehan, J F, Feng, Z, Kapur, V, Barletta, R G
フォーマット: Artigo
言語:Inglês
出版事項: 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC179361/
https://ncbi.nlm.nih.gov/pubmed/9260945
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