Overexpression of the D-alanine racemase gene confers resistance to D-cycloserine in Mycobacterium smegmatis.
D-Cycloserine is an effective second-line drug against Mycobacterium avium and Mycobacterium tuberculosis. To analyze the genetic determinants of D-cycloserine resistance in mycobacteria, a library of a resistant Mycobacterium smegmatis mutant was constructed. A resistant clone harboring a recombina...
Kaydedildi:
| Yayımlandı: | J Bacteriol |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Microbiology (ASM)
1997
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179361/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9260945/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.179.16.5046-5055.1997 |
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