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Amyloid-like aggregates of neuronal tau induced by formaldehyde promote apoptosis of neuronal cells

BACKGROUND: The microtubule associated protein tau is the principle component of neurofibrillar tangles, which are a characteristic marker in the pathology of Alzheimer's disease; similar lesions are also observed after chronic alcohol abuse. Formaldehyde is a common environmental contaminant a...

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Detalhes bibliográficos
Main Authors: Nie, Chun Lai, Wang, Xing Sheng, Liu, Ying, Perrett, Sarah, He, Rong Qiao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1790706/
https://ncbi.nlm.nih.gov/pubmed/17241479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-8-9
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