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A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1

The Stat1 activation-inactivation cycle involves phosphorylation of Stat1 in the cytoplasm, translocation to the nucleus, and then a return of the protein to the cytoplasm in a dephosphorylated state. However, the intracellular site of Stat1 dephosphorylation has not been determined. As receptor sig...

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Библиографические подробности
Главные авторы: Haspel, Richard L., Darnell, James E.
Формат: Artigo
Язык:Inglês
Опубликовано: The National Academy of Sciences 1999
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC17864/
https://ncbi.nlm.nih.gov/pubmed/10468584
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