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A nuclear protein tyrosine phosphatase is required for the inactivation of Stat1

The Stat1 activation-inactivation cycle involves phosphorylation of Stat1 in the cytoplasm, translocation to the nucleus, and then a return of the protein to the cytoplasm in a dephosphorylated state. However, the intracellular site of Stat1 dephosphorylation has not been determined. As receptor sig...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Haspel, Richard L., Darnell, James E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17864/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10468584/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.18.10188
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