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Mitochondrial DNA sequence variation in single cells from leukemia patients
A high frequency of mtDNA somatic mutation has been observed in many tumors as well as in aging tissues. In this study, we analyzed the mtDNA control region sequence variation in 3534 single normal cells and individual blasts from 18 patients with leukemia and 10 healthy donors, to address the mutat...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1785100/ https://ncbi.nlm.nih.gov/pubmed/16946307 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-01-011007 |
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