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Accumulation of mtDNA variations in human single CD34(+) cells from maternally related individuals: effects of aging and family genetic background
Marked sequence variation in the mtDNA control region has been observed in human single CD34(+) cells, which persist in vivo and are present also in differentiated hematopoietic cells. In this study, we analyzed 5071 single CD34(+) cells from 49 individuals (including 31 maternally related members f...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4154056/ https://ncbi.nlm.nih.gov/pubmed/23455392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2013.01.006 |
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