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The β-globin promoter is important for recruitment of erythroid Krüppel-like factor to the locus control region in erythroid cells

Erythroid Krüppel-like factor (EKLF), which binds to the CACCC box in the β-globin promoter, is required for the expression of the β-globin gene in adult erythroid cells. It was recently demonstrated that EKLF is also required for the activity of the β-globin locus control region (LCR) 5′HS3. Some e...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lee, Jong-Soo, Lee, Chang-Hun, Chung, Jay H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC17840/
https://ncbi.nlm.nih.gov/pubmed/10468560
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