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The β-globin promoter is important for recruitment of erythroid Krüppel-like factor to the locus control region in erythroid cells

Erythroid Krüppel-like factor (EKLF), which binds to the CACCC box in the β-globin promoter, is required for the expression of the β-globin gene in adult erythroid cells. It was recently demonstrated that EKLF is also required for the activity of the β-globin locus control region (LCR) 5′HS3. Some e...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Lee, Jong-Soo, Lee, Chang-Hun, Chung, Jay H.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17840/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10468560/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.18.10051
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