The β-globin promoter is important for recruitment of erythroid Krüppel-like factor to the locus control region in erythroid cells
Erythroid Krüppel-like factor (EKLF), which binds to the CACCC box in the β-globin promoter, is required for the expression of the β-globin gene in adult erythroid cells. It was recently demonstrated that EKLF is also required for the activity of the β-globin locus control region (LCR) 5′HS3. Some e...
Uloženo v:
| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1999
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17840/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10468560/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.18.10051 |
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