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The β-globin promoter is important for recruitment of erythroid Krüppel-like factor to the locus control region in erythroid cells
Erythroid Krüppel-like factor (EKLF), which binds to the CACCC box in the β-globin promoter, is required for the expression of the β-globin gene in adult erythroid cells. It was recently demonstrated that EKLF is also required for the activity of the β-globin locus control region (LCR) 5′HS3. Some e...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The National Academy of Sciences
1999
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC17840/ https://ncbi.nlm.nih.gov/pubmed/10468560 |
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