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Synthesis and evaluation of 3-aminopropionyl substituted fentanyl analogues for opioid activity

An enkephalin analogue coupled to ‘aminofentanyl’ has been synthesized and tested for biological activities at the μ and δ opioid receptors. Aminofentanyl which represents a structural derivative of fentanyl has been synthesized by acylation of 1-(2-phenethyl)-4-(N-anilino)piperidine with phthaloyl...

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Autores principales: Petrov, Ravil R., Vardanyan, Ruben S., Lee, Yeon S., Ma, Shou-wu, Davis, Peg, Begay, Lucinda J., Lai, Josephine Y., Porreca, Frank, Hruby, Victor J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783977/
https://ncbi.nlm.nih.gov/pubmed/16828552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2006.06.040
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