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Disulfide Trapping the Mechanosensitive Channel MscL into a Gating-Transition State

The mechanosensitive channel of large conductance, MscL, serves as a biological emergency release valve protecting bacteria from acute osmotic downshock, and is to date the best characterized mechanosensitive channel. The N-terminal region of the protein has been shown to be critical for function by...

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Autores principales: Iscla, Irene, Levin, Gal, Wray, Robin, Blount, Paul
Formato: Artigo
Lenguaje:Inglês
Publicado: Biophysical Society 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783893/
https://ncbi.nlm.nih.gov/pubmed/17114217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.090316
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