Acetylphosphinate is the most potent mechanism-based substrate-like inhibitor of both the human and E. coli pyruvate dehydrogenase components of the pyruvate dehydrogenase complex

Lignende værker

• Binding of pyruvate dehydrogenase to the core of the human pyruvate dehydrogenase complex
  af: Korotchkina, Lioubov G., et al.
  Udgivet: (2008)
• Interaction of E1 and E3 components with the core proteins of the human pyruvate dehydrogenase complex
  af: Patel, Mulchand S., et al.
  Udgivet: (2009)
• Pyruvate dehydrogenase complex deficiency is linked to regulatory loop disorder in the αV138M variant of human pyruvate dehydrogenase
  af: Whitley, Matthew J., et al.
  Udgivet: (2018)
• The Pyruvate Dehydrogenase Complexes: Structure-based Function and Regulation
  af: Patel, Mulchand S., et al.
  Udgivet: (2014)
• The 1′,4′-iminopyrimidine tautomer of thiamin diphosphate is poised for catalysis in asymmetric active centers on enzymes
  af: Nemeria, Natalia, et al.
  Udgivet: (2007)