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Conversions of Formaldehyde-modified 2′-Deoxyadenosine 5′-Monophosphate in Conditions Modeling Formalin-fixed Tissue Dehydration

Formalin-fixed, paraffin-embedded specimens typically provide molecular biologists with low yields of extractable nucleic acids that exhibit extensive strand cleavage and covalent modification of nucleic acid bases. This study supports the idea that these deleterious effects are promoted by the firs...

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Main Authors: Rait, Vladimir K., Zhang, Qingrong, Fabris, Daniele, Mason, Jeffrey T., O’Leary, Timothy J.
Format: Artigo
Jezik:Inglês
Izdano: 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783762/
https://ncbi.nlm.nih.gov/pubmed/16116034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/jhc.5A6725.2005
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