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Modeling formalin fixation and antigen retrieval with bovine pancreatic ribonuclease A: I—Structural and functional alterations

Understanding the chemistry of protein modification by formaldehyde is central to developing improved methods to recover proteins from formalin-fixed paraffin-embedded tissues for proteomic analysis and to improve protein immunoreactivity for immunohistochemical studies. We used biophysical techniqu...

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Detalhes bibliográficos
Main Authors: Rait, Vladimir K, O’Leary, Timothy J, Mason, Jeffrey T
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1747597/
https://ncbi.nlm.nih.gov/pubmed/14968117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.3700045
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