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The dynamin middle domain is critical for tetramerization and higher-order self-assembly

The large multidomain GTPase dynamin self-assembles around the necks of deeply invaginated coated pits at the plasma membrane and catalyzes vesicle scission by mechanisms that are not yet completely understood. Although a structural role for the ‘middle' domain in dynamin function has been sugg...

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Главные авторы: Ramachandran, Rajesh, Surka, Mark, Chappie, Joshua S, Fowler, Douglas M, Foss, Ted R, Song, Byeong Doo, Schmid, Sandra L
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783472/
https://ncbi.nlm.nih.gov/pubmed/17170701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601491
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