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An internal GAP domain negatively regulates presynaptic dynamin in vivo: a two-step model for dynamin function
The mechanism by which the self-assembling GTPase dynamin functions in vesicle formation remains controversial. Point mutations in shibire, the Drosophila dynamin, cause temperature-sensitive (ts) defects in endocytosis. We show that the ts2 mutation, which occurs in the switch 2 region of dynamin&#...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2005
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171915/ https://ncbi.nlm.nih.gov/pubmed/15824135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200502042 |
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