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WIP is a chaperone for Wiskott–Aldrich syndrome protein (WASP)

Wiskott–Aldrich syndrome protein (WASP) is in a complex with WASP-interacting protein (WIP). WASP levels, but not mRNA levels, were severely diminished in T cells from WIP(−/−) mice and were increased by introduction of WIP in these cells. The WASP binding domain of WIP was shown to protect WASP fro...

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Autors principals: de la Fuente, Miguel A., Sasahara, Yoji, Calamito, Marco, Antón, Inés M., Elkhal, Abdallah, Gallego, Maria D., Suresh, Koduru, Siminovitch, Katherine, Ochs, Hans D., Anderson, Kenneth C., Rosen, Fred S., Geha, Raif S., Ramesh, Narayanaswamy
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783416/
https://ncbi.nlm.nih.gov/pubmed/17213309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0610275104
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