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Highly efficient endonucleolytic cleavage of RNA by a Cys(2)His(2) zinc-finger peptide

We have identified a 30-aa peptide that efficiently cleaves single-stranded RNA. The peptide sequence corresponds to a single zinc finger of the human male-associated ZFY protein; a transcription factor belonging to the Cys(2)His(2) family of zinc-finger proteins. RNA cleavage was observed only in t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lima, Walt F., Crooke, Stanley T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC17833/
https://ncbi.nlm.nih.gov/pubmed/10468553
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