Nitric oxide protects cultured rheumatoid synovial cells from Fas-induced apoptosis by inhibiting caspase-3

Nitric oxide (NO) is elevated in the synovial fluids and sera of patients with rheumatoid arthritis (RA) and is thought to be an important proinflammatory mediator in the rheumatoid synovium. To test the hypothesis that NO might modulate the apoptosis-inducing signal pathway, we investigated the eff...

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Detalhes bibliográficos
Main Authors: Migita, Kiyoshi, Yamasaki, Satoshi, Kita, Masako, Ida, Hiroaki, Shibatomi, Kazutaka, Kawakami, Atsushi, Aoyagi, Takahiko, Eguchi, Katsuni
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783248/
https://ncbi.nlm.nih.gov/pubmed/11454065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2001.01252.x
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