Regulation of rheumatoid synoviocyte proliferation by endogenous p53 induction

The p53 tumour suppressor protein protects cells from tumorigenic alterations by inducing either cell growth arrest or apoptosis. In the present study, we investigated the role of endogenous p53 expressed in rheumatoid arthritis synovial fibroblasts which show transformed-appearing phenotypes. Type...

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Detalhes bibliográficos
Main Authors: Migita, K, Tanaka, F, Yamasaki, S, Shibatomi, K, Ida, H, Kawakami, A, Aoyagi, T, Kawabe, Y, Eguchi, K
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Rheumatic Disease/Vasculitis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1906196/
https://ncbi.nlm.nih.gov/pubmed/11703379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2249.2001.01677.x
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