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Adjuvant effects of CpG oligodeoxynucleotides on responses against T-independent type 2 antigens

Oligodeoxynucleotides containing CpG motifs (CpG-ODN) are potent in vitro B-cell activators and they have been successfully used to increase in vivo antibody responses to T-dependent peptide and protein antigens. In contrast, the use of CpG-ODN to enhance in vivo antibody responses to various T-inde...

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Autors principals: Kovarik, J, Bozzotti, P, Tougne, C, Davis, H L, Lambert, P -H, Krieg, A M, Siegrist, C -A
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783157/
https://ncbi.nlm.nih.gov/pubmed/11168639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2001.01158.x
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