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Functional activity of CD40 antibodies correlates to the position of binding relative to CD154

In this study we describe the characterization of a panel of 12 anti-mouse CD40 monoclonal antibodies (mAb). Characterization was performed in terms of antibody-binding site relative to the CD154 ligand, and the relationship between position and functional outcome of binding. The antibodies divided...

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Autores principales: Barr, T A, Heath, A W
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783151/
https://ncbi.nlm.nih.gov/pubmed/11168635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2001.01148.x
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