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Dendritic cell maturation enhances CD8(+) T-cell responses to exogenous antigen via a proteasome-independent mechanism of major histocompatibility complex class I loading

Immune stimulating complexes (ISCOMS) containing the saponin adjuvant Quil A are vaccine adjuvants that induce a wide range of immune responses in vivo, including strong class I major histocompatibility complex (MHC) -restricted cytotoxic T-lymphocyte activity. However, the antigen-presenting cell r...

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Autors principals: Robson, Neil C, Beacock-Sharp, Helen, Donachie, Anne M, Mowat, Allan McI
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782973/
https://ncbi.nlm.nih.gov/pubmed/12807483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01664.x
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