Soluble FcγRIIa inhibits rheumatoid factor binding to immune complexes

Soluble low-affinity receptors for IgG are known to inhibit immune complex (IC)-mediated inflammation, and expression by leukocytes is elevated in several inflammatory diseases. Immunoglobulin M (IgM) rheumatoid factors (RF), anti-Fc autoantibodies, are found in autoimmune diseases, such as rheumato...

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Autors principals: Wines, Bruce D, Gavin, Amanda, Powell, Maree S, Steinitz, Michael, Buchanan, Russell R C, Hogarth, P Mark
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Inc 2003
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782965/
https://ncbi.nlm.nih.gov/pubmed/12757620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01652.x
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