The Rare Anaphylaxis-Associated FcγRIIa3 Exhibits Distinct Characteristics From the Canonical FcγRIIa1

FcγRIIa is an activating FcγR, unique to humans and non-human primates. It induces antibody-dependent proinflammatory responses and exists predominantly as FcγRIIa1. A unique splice variant, we designated FcγRIIa3, has been reported to be associated with anaphylactic reactions to intravenous immunog...

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發表在:Front Immunol
Main Authors: Anania, Jessica C., Trist, Halina M., Palmer, Catherine S., Tan, Peck Szee, Kouskousis, Betty P., Chenoweth, Alicia M., Kent, Stephen J., Mackay, Graham A., Hoi, Alberta, Koelmeyer, Rachel, Slade, Charlotte, Bryant, Vanessa L., Hodgkin, Philip D., Aui, Pei Mun, van Zelm, Menno C., Wines, Bruce D., Hogarth, P. Mark
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109644/
https://ncbi.nlm.nih.gov/pubmed/30177930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01809
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