The Rare Anaphylaxis-Associated FcγRIIa3 Exhibits Distinct Characteristics From the Canonical FcγRIIa1

FcγRIIa is an activating FcγR, unique to humans and non-human primates. It induces antibody-dependent proinflammatory responses and exists predominantly as FcγRIIa1. A unique splice variant, we designated FcγRIIa3, has been reported to be associated with anaphylactic reactions to intravenous immunog...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Anania, Jessica C., Trist, Halina M., Palmer, Catherine S., Tan, Peck Szee, Kouskousis, Betty P., Chenoweth, Alicia M., Kent, Stephen J., Mackay, Graham A., Hoi, Alberta, Koelmeyer, Rachel, Slade, Charlotte, Bryant, Vanessa L., Hodgkin, Philip D., Aui, Pei Mun, van Zelm, Menno C., Wines, Bruce D., Hogarth, P. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109644/
https://ncbi.nlm.nih.gov/pubmed/30177930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.01809
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