Structural Basis for FcγRIIa Recognition of Human IgG and Formation of Inflammatory Signaling Complexes

The interaction of Abs with their specific FcRs is of primary importance in host immune effector systems involved in infection and inflammation, and are the target for immune evasion by pathogens. FcγRIIa is a unique and the most widespread activating FcR in humans that through avid binding of immun...

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Hauptverfasser: Ramsland, Paul A., Farrugia, William, Bradford, Tessa M., Tan Sardjono, Caroline, Esparon, Sandra, Trist, Halina M., Powell, Maree S., Szee Tan, Peck, Cendron, Angela C., Wines, Bruce D., Scott, Andrew M., Hogarth, P. Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3282893/
https://ncbi.nlm.nih.gov/pubmed/21856937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101467
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