Functional and phenotypic studies of two variants of a human mast cell line with a distinct set of mutations in the c-kit proto-oncogene

The human mast cell line (HMC)-1 cell line is growth-factor independent because of a constitutive activity of the receptor tyrosine kinase Kit. Such deregulated Kit activity has also been suggested causative in gastrointestinal stromal tumours (GISTs) and mastocytosis. HMC-1 is the only established...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Sundström, Magnus, Vliagoftis, Harissios, Karlberg, Peter, Butterfield, Joseph H, Nilsson, Kenneth, Metcalfe, Dean D, Nilsson, Gunnar
פורמט: Artigo
שפה:Inglês
יצא לאור: Blackwell Science Inc 2003
נושאים:
Original Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782858/
https://ncbi.nlm.nih.gov/pubmed/12519307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2003.01559.x
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים