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Predicting Phenotypic Severity of Uncertain Gene Variants in the RET Proto-Oncogene
Although reported gene variants in the RET oncogene have been directly associated with multiple endocrine neoplasia type 2 and hereditary medullary thyroid carcinoma, other mutations are classified as variants of uncertain significance (VUS) until the associated clinical phenotype is made clear. Cur...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3068179/ https://ncbi.nlm.nih.gov/pubmed/21479187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018380 |
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