Loss of CD154 impairs the Th2 extrafollicular plasma cell response but not early T cell proliferation and interleukin-4 induction

Ligation of CD40 by CD4 T cells through CD154 is key both to germinal centre induction and follicular T-dependent Ig class switching, but its requirement for aspects of T cell priming and extrafollicular antibody responses is less clear. Here comparison of the T helper (Th) type 2 response in lymph...

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Hlavní autoři: Cunningham, Adam F, Serre, Karine, Mohr, Elodie, Khan, Mahmood, Toellner, Kai-Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2004
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782567/
https://ncbi.nlm.nih.gov/pubmed/15379979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01951.x
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