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Enhancement of the synthetic ligand-mediated function of liver NK1.1Ag(+) T cells in mice by interleukin-12 pretreatment

We previously reported that mouse NK1.1 Ag(+) T (NKT) cells activated by interleukin-12 (IL-12) act as anti-tumour/anti-metastatic effectors. However, IL-12 reportedly induces a rapid disappearance of liver NKT cells by activation-induced apoptosis. In the present study, however, we show that inject...

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Bibliografiske detaljer
Main Authors: Habu, Yoshiko, Uchida, Takefumi, Inui, Takuo, Nakashima, Hiroyuki, Fukasawa, Masashi, Seki, Shuhji
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2004
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782545/
https://ncbi.nlm.nih.gov/pubmed/15312134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01932.x
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