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The Effect of Synthetic C-Reactive Protein on the In Vitro Immune Response of Human PBMCs Stimulated with Bacterial Reagents

Synthetic C-reactive protein (CRP) rescues mice from lethal endotoxin shock or bacterial infection by suppressing tumor necrosis factor (TNF-α), but in turn, enhances Kupffer cell phagocytic activity. We herein assessed the influence of CRP in human peripheral blood mononuclear cells (PBMCs). When h...

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Bibliografiske detaljer
Main Authors: Sato, Atsushi, Nakashima, Hiroyuki, Kinoshita, Manabu, Nakashima, Masahiro, Ogawa, Yoshiko, Shono, Satoshi, Ikarashi, Masami, Seki, Shuhji
Format: Artigo
Sprog:Inglês
Udgivet: Springer US 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708291/
https://ncbi.nlm.nih.gov/pubmed/23407995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10753-013-9604-4
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