Reversal of established CD4(+) type 2 T helper-mediated allergic airway inflammation and eosinophilia by therapeutic treatment with DNA vaccines limits progression towards chronic inflammation and remodelling

Immunostimulatory DNA-based vaccines can prevent the induction of CD4(+) type 2 T helper (Th2) cell-mediated airway inflammation in experimental models, when administered before or at the time of allergen exposure. Here we demonstrate their efficacy in limiting the progression of an established resp...

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Bibliographic Details
Main Authors: Jarman, Elizabeth R, Lamb, Jonathan R
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2004
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782528/
https://ncbi.nlm.nih.gov/pubmed/15270735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01927.x
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