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Reversal of established CD4(+) type 2 T helper-mediated allergic airway inflammation and eosinophilia by therapeutic treatment with DNA vaccines limits progression towards chronic inflammation and remodelling

Immunostimulatory DNA-based vaccines can prevent the induction of CD4(+) type 2 T helper (Th2) cell-mediated airway inflammation in experimental models, when administered before or at the time of allergen exposure. Here we demonstrate their efficacy in limiting the progression of an established resp...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Jarman, Elizabeth R, Lamb, Jonathan R
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2004
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782528/
https://ncbi.nlm.nih.gov/pubmed/15270735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01927.x
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