4-1BB and OX40 stimulation enhance CD8 and CD4 T-cell responses to a DNA prime, poxvirus boost vaccine

4-1BB (CD137) is a tumour necrosis factor receptor (TNFR) family member, expressed primarily on CD8 T cells after activation. Signalling through 4-1BB has been reported to enhance CD8 T-cell expansion and to protect activated CD8 T cells from death, resulting in an enlarged memory population. Althou...

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Autors principals: Munks, Michael W, Mourich, Dan V, Mittler, Robert S, Weinberg, Andrew D, Hill, Ann B
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2004
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782516/
https://ncbi.nlm.nih.gov/pubmed/15270726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01917.x
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