Elevated interferon gamma expression in the central nervous system of tumour necrosis factor receptor 1-deficient mice with experimental autoimmune encephalomyelitis

Inflammation in the central nervous system (CNS) can be studied in experimental autoimmune encephalomyelitis (EAE). The proinflammatory cytokines interferon-gamma (IFN-γ) and tumour necrosis factor (TNF) are implicated in EAE pathogenesis. Signals through the type 1 TNF receptor (TNFR1) are required...

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Autori principali: Wheeler, Rachel D, Zehntner, Simone P, Kelly, Lisa M, Bourbonnière, Lyne, Owens, Trevor
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2006
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782311/
https://ncbi.nlm.nih.gov/pubmed/16780563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02395.x
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