Stage-Specific Role of Interferon-Gamma in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

The role of interferon (IFN)-γ in multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE), has remained as an enigmatic paradox for more than 30 years. Several studies attribute this cytokine a prominent proinflammatory and pathogenic function in these pathologi...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Arellano, Gabriel, Ottum, Payton A., Reyes, Lilian I., Burgos, Paula I., Naves, Rodrigo
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2015
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586507/
https://ncbi.nlm.nih.gov/pubmed/26483787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2015.00492
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