Extended sequence preferences for oligodeoxyribonucleotide activity

Synthetic type B phosphorothioate oligodeoxyribonucleotides (ODN) activate mouse B cells via Toll-like receptor 9 (TLR9). Starting with closely related 15-mer prototype ODN, the sequence requirements for stimulatory (ST-) and inhibitory (IN-) activity were contrasted, by measuring apoptosis protecti...

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Main Authors: Lenert, Petar, Goeken, Adam J, Ashman, Robert F
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2006
Assuntos:
Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782261/
https://ncbi.nlm.nih.gov/pubmed/16556261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02320.x
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