Lipoteichoic acid induces nuclear factor-κB activation and nitric oxide synthase expression via phosphatidylinositol 3-kinase, Akt, and p38 MAPK in RAW 264.7 macrophages

We previously demonstrated that lipoteichoic acid (LTA) might activate phosphatidylcholine-phospholipase C (PC-PLC) and phosphatidylinositol-phospholipase C (PI-PLC) to induce protein kinase C activation, which in turn initiates nuclear factor-κB (NF-κB) activation and finally induces inducible nitr...

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Hlavní autoři: Kao, Shang-Jyh, Lei, Hui-Chieh, Kuo, Chen-Tzu, Chang, Ming-Shyan, Chen, Bing-Chang, Chang, Yau-Chong, Chiu, Wen-Ta, Lin, Chien-Huang
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2005
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782163/
https://ncbi.nlm.nih.gov/pubmed/15946254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02160.x
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