Identification and characterization of a functional, alternatively spliced Toll-like receptor 7 (TLR7) and genomic disruption of TLR8 in chickens

Based upon the recognition of antiviral compounds and single stranded viral RNA the Toll-like receptors TLR7 and TLR8 are suggested to play a significant role in initiating antiviral immune responses. Here we report the molecular characterization of the chicken TLR7/8 loci which revealed an intact T...

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Autors principals: Philbin, Victoria J, Iqbal, Muhammad, Boyd, Yvonne, Goodchild, Marianne J, Beal, Richard K, Bumstead, Nat, Young, John, Smith, Adrian L
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2005
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782111/
https://ncbi.nlm.nih.gov/pubmed/15804288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02125.x
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