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Toll-Like Receptor 9 Alternatively Spliced Isoform Negatively Regulates TLR9 Signaling in Teleost Fish

Toll-like receptor 9 (TLR9) recognizes and binds unmethylated CpG motifs in DNA, which are found in the genomes of bacteria and DNA viruses. In fish, Tlr9 is highly diverse, with the number of introns ranging from 0 to 4. A fish Tlr9 gene containing two introns has been reported to express two alter...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lee, Frank Fang-Yao, Chuang, Hsiang-Chieh, Chen, Nai-Yu, Nagarajan, Govindarajulu, Chiou, Pinwen Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4425437/
https://ncbi.nlm.nih.gov/pubmed/25955250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126388
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